Sean McCabe

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Assistant Professor, Department of Biostatistics and Health Data Sciences, Indiana University School of Medicine

Biography

The McCabe Lab develops bioinformatic tools and statistical methodology for high dimensional genomic datasets to help elucidate disease severity mechanisms; application areas include Multiple Myeloma, prostate cancer, rare cancer detection, and sepsis development. Since 2023, the McCabe lab has submitted several proposals and papers and is on track to have several additional submissions before the end of the year. Dr. McCabe has recently made external connections with Eli Lilly and is currently working on two projects involving genomic and genetic data. Dr. McCabe has received funding for the analysis of the Indiana Biobank in collaboration with investigators at IUSM & at Eli Lilly. Another contract with Eli Lilly will be in collaboration with Travis Johnson at IBRI (an AnalytiXIN faculty member) to perform an analysis of single cell datasets collected for both ATAC and RNA-seq.

The AnalytiXIN funding has supported Dr. McCabe in hiring Rameesha Syed, a first year PhD student who recently graduated from the Luddy School and will support an additional student hire in the fall of 2024; these students help propel research forward by assisting in data set analysis. This funding has also given Dr. McCabe resources to apply for NIH grants and other funding mechanisms to help support a self-sustaining lab.

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