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Brett Meyers is a research scientist with Purdue University's Regenstrief Center for Healthcare Engineering, who is focusing on multidisciplinary research to improve healthcare for underrepresented populations and to improve patient outcomes. His primary research involves experimental biofluids and biomechanics aiming to understand the impact of hydrodynamics and mechanics on physiological systems. This work has led to the development of innovative methods, instruments, and data analysis tools, which is improving diagnostic capabilities in clinical practice. He also serves as Assistant Director for Eli Lilly and Company and Purdue University Research Alliance Center (LPRC), focusing on generating new opportunities for undergraduate research in pharmaceutical and drug delivery projects aligned with this partnership.
Dr. Meyers received a B.S. in Mechanical Engineering from Drexel University (2011); his senior thesis focused on microfabrication of a multi-chamber chip for isolating single cells to study low Reynolds number swimming. He earned an M.S. in Mechanical Engineering from Virginia Tech (2014); his thesis work focused on studying left heart filling function. This study devised a novel method to track the motion of gas-filled microbubbles introduced into the bloodstream commonly used to enhance the visualization of heart chambers in patients with limited myocardial tissue boundary signals in echocardiograms. He earned a Ph.D. in Mechanical Engineering from Purdue University (2021); his dissertation focused on novel methods to resolve biofluids and biomechanics measurements from echocardiograms, forming the foundation for his current software platform. Other postdoctoral studies at Purdue University he was involved in focused on studying methods for collecting digital biomarkers from various devices.
Dr. Meyers has authored or coauthored over a dozen journal papers and more than 30 refereed papers in conference proceedings and extended abstracts, with over 100 citations and an h-index of 5. His work has resulted in multiple intellectual property disclosures and patents, 4 that are licensed. As key personnel, he contributed to over a dozen externally funded research project proposals, with over $300,000 awarded. Throughout his Ph.D. and postdoctoral training, he mentored three undergraduate researchers and a capstone project team. Currently, he mentors more than a dozen students in the Vlachos Research Group and oversees two undergraduate research teams – one capstone project and one vertically integrated project.
In his current work, Dr. Meyers leads collaborative efforts to advance a software platform for semi-autonomous and autonomous measurements of cardiac biomechanics from echocardiograms, encompassing standard and novel parameters used in patient diagnosis. The platform, designed for various patient populations from fetus to adult, empowers non-experts to easily obtain these parameters, addressing limitations in accessibility and expertise. His work also spans advanced statistical analysis of healthcare data to assess care strategy impact on patients facing significant barriers to care and building a comprehensive understanding of the drug delivery process for central nervous system targeted therapy.
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